cialis order online It was observed that combination therapy involving the
blockade of the leptin receptor and treatment with tamoxifen could inhibit
proliferation and promote apoptosis in breast cancer cells resistant to
tamoxifen, suggesting that the suppression of leptin could be a new means to
circumvent resistance to antiestrogenic treatment in breast cancer, because
the signaling pathways activated by leptin could directly participate in the
cellular response to the chemotherapeutic treatment 12
